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SURGE
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Revision date
08/08/2008
11. TOXICOLOGICAL INFORMATION
No data is available for this material.
The information shown is for 2-Butoxyethanol which is present at less than 12%.
Toxicity Data
Oral LD50 Rat: 470mg/Kg. Skin LD50 Rabbit: 220mg/Kg. Inhaled LC50 Rat: 2211mg/m
3
(4hr).
Skin Irritation Rabbit: Slight irritation. Eye Irritation: Irritation.
Note: No studies are available on the effects of long term exposure in humans. Studies indicate that
repeated exposure causes blood, liver and kidney disorders in animals. Deaths in acute studies were
generally caused by narcosis or respiratory failure, with kidney failure seen as a secondary cause.
The main toxic effect observed in acute and repeated dose animal studies is haemolysis. The effect
varies between species with rats and mice the most susceptible, rabbits less susceptible and guinea-
pigs and humans least susceptible. Changes in kidney, liver, spleen and lungs were found in
animals exposed by ingestion, inhalation and skin absorption. Deaths usually result from CNS
depression, lung damage and kidney injury.
Health Effects – Acute
Swallowed
Harmful if swallowed. Ingestion may cause irritation of mucous membranes in mouth, pharynx,
oesophagus and gastro-intestinal tracts. Symptoms include nausea, headache, vomiting, ataxia
(impaired locomotor co-ordination), acidosis, drowsiness,
Agitation, insomnia, changes in the blood picture, pulmonary oedema and damage to the liver and
kidneys.
Eye
Causes eye irritation.
Skin
May be harmful by prolonged contact with skin. Danger of skin absorption. Irritating to skin.
Inhaled
Inhalation causes irritation to the mucus membranes, coughing and dyspnoea. Chronic exposure
causes damage to blood cells and blood in urine.
12. ECOLOGICAL INFORMATION
Ecotoxicity:
No data available
Persistence and degradability:
No information available for this product.
Mobility:
No information available on this product.
Additional information
Environmental fate (exposure):
Avoid contaminating waterways, drains and sewers.
Bioaccumulative potential:
No information available for this product.