Research Products MSDS

MELT DOWN

Page 4 of 6

Revision date

08/08/2008

10. STABILITY & REACTIVITY

Hazardous Reactions

Product is stable under normal conditions of use,

storage and temperature.

Materials to avoid:

Do not store in aluminium containers.

Polymerization:

Product will not undergo polymerization.

11. TOXICOLOGICAL INFORMATION

No data is available for this material. The information shown is for ethylene glycol mono butyl

ether which is present at less than 25%.

Toxicity Data

Oral LD50 Rat: 470mg/Kg. Skin LD50 Rabbit: 220mg/Kg. Inhaled LC50 Rat: 2211mg/m

(4hr).

Skin Irritation Rabbit: Slight irritation. Eye Irritation: Irritation.

Note: No studies are available on the effects of long term exposure in humans. Studies indicate

that repeated exposure causes blood, liver and kidney disorders in animals. Deaths in acute

studies were generally caused by narcosis or respiratory failure, with kidney failure seen as a

secondary cause.

The main toxic effect observed in acute and repeated dose animal studies is haemolysis. The

effect varies between species with rats and mice the most susceptible, rabbits less susceptible

and guinea-pigs and humans least susceptible. Changes in kidney, liver, spleen and lungs were

found in animals exposed by ingestion, inhalation and skin absorption. Deaths usually result

from CNS depression, lung damage and kidney injury.

Health Effects – Acute

Swallowed

May be harmful if swallowed. Ingestion may cause irritation of mucous membranes in mouth,

pharynx, oesophagus and gastro-intestinal tracts. Symptoms include nausea, headache, vomiting,

ataxia (impaired locomotor co-ordination), acidosis, drowsiness,

Agitation, insomnia, changes in the blood picture, pulmonary oedema and damage to the liver

and kidneys.

Eye

Causes eye irritation.

Skin

Irritating to skin. Danger of skin absorption.

Inhaled

Inhalation causes irritation to the mucus membranes, coughing and dyspnoea. Chronic exposure

causes damage to blood cells and blood in urine.